HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Secondary chronic cluster headache treated by posterior hypothalamic deep brain stimulation: first reported case.

AbstractINTRODUCTION:
Deep brain stimulation (DBS) of the posterior hypothalamus (pHyp) has been reported as an effective treatment for primary, drug-refractory and chronic cluster headache (CCH). We here describe the use of such a procedure for the treatment of secondary CCH due to a neoplasm affecting the soft tissues of the right hemiface.
METHODS:
A 27-year-old man affected by infiltrating angiomyolipoma of the right hemiface who subsequently developed drug refractory homolateral CCH underwent DBS of the right pHyp region at the Fondazione IRCCS Istituto Nazionale Neurologico Carlo Besta.
RESULTS:
After surgery, the patient presented a significant reduction in frequency of pain bouts. However, because of a subsequent infection, the entire system was removed. After re-implantation of the system, successful outcome was observed at 2 years follow-up.
DISCUSSION:
This brief report shows the feasibility of pHyp DBS in secondary drug-refractory CCH syndromes; future reports are needed in order to confirm our positive result.
AuthorsGiuseppe Messina, Michele Rizzi, Roberto Cordella, Augusto Caraceni, Ernesto Zecca, Gennaro Bussone, Angelo Franzini, Massimo Leone
JournalCephalalgia : an international journal of headache (Cephalalgia) Vol. 33 Issue 2 Pg. 136-8 (Jan 2013) ISSN: 1468-2982 [Electronic] England
PMID23165695 (Publication Type: Case Reports, Journal Article)
Topics
  • Adult
  • Cluster Headache (diagnosis, therapy)
  • Deep Brain Stimulation (methods)
  • Headache Disorders, Secondary (diagnosis, prevention & control)
  • Humans
  • Hypothalamus
  • Male
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: