Collagen matrix injection combined with flap repair for complex anal fistula.

Abstract

Several biomaterials have been proposed to treat anal fistula alone or in combination with other surgical procedures aiming to reduce recurrence rates while minimizing continence impairment. More recently a porcine dermal matrix injection has been proposed as infill biomaterial to treat fistulae. We propose an approach consisting of non-cutting seton positioning followed several weeks later by flap repair associated with dermal matrix injection into the fistula tracts. We report our experience with this two-staged procedure on 24 consecutive patients with complex anal fistulae with a median follow up of > 12 months. In our experience this two-stage approach seems to be safe and effective.

• Authors: P Sileri, G Boehm, L Franceschilli, F Giorgi, F Perrone, C Stolfi, G Monteleone, A L Gaspari
• Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (Colorectal Dis) Vol. 14 Suppl 3 Pg. 24-8 (Dec 2012) ISSN: 1463-1318 [Electronic] England
• PMID: 23136821 (Publication Type: Journal Article)
• Copyright: © 2012 The Authors. Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland.

Chemical References

• Permacol
• Collagen

Topics

• Adult
• Aged
• Collagen (administration & dosage)
• Combined Modality Therapy
• Female
• Follow-Up Studies
• Humans
• Injections
• Middle Aged
• Pain Measurement
• Postoperative Complications
• Rectal Fistula (surgery)
• Recurrence
• Surgical Flaps
• Treatment Outcome
• Young Adult