Results of intravenous steroid injection on reduction of postoperative edema in rhinoplasty.

Abstract

OBJECTIVE:

To determine the efficacy of intravenous dexamethasone in reducing postrhinoplasty edema.

DESIGN:

A prospective, randomized clinical trial with placebo control.

SETTING:

Department of Otorhinolaryngology, Al-Sabah and Zain Hospital, Kuwait.

SUBJECT:

Eighty-four patients (male = 28; female = 56) aged between 20 and 40 years, undergoing open rhinoplasty with hump removal and bilateral lateral osteotomies were enrolled in this study.

INTERVENTION:

Patients were randomized to receive two doses of 10 mg of dexamethasone intravenously or placebo, first dose during surgery and second dose 12 hours after surgery.

MAIN OUTCOME MEASURES:

Patients were evaluated postoperatively at 24 hours, days 2, 5, 7 and 10 for periorbital edema.

RESULTS:

10 mg of dexamethasone given intravenously during rhinoplasty and a second dose 12 hours after surgery, reduced postoperative periorbital edema significantly.

CONCLUSION:

This study showed a statistically significant benefit of dexamethasone over placebo in reducing periorbital edema after rhinoplasty. No complications were attributed to the administration of dexamethasone.

• Authors: Monther Ali Alajmi, Khalid A Al-Abdulhadi, Hamoud Saud Al-Noumas, Gopalan Kavitha
• Journal: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India (Indian J Otolaryngol Head Neck Surg) Vol. 61 Issue 4 Pg. 266-9 (Dec 2009) ISSN: 2231-3796 [Print] India
• PMID: 23120648 (Publication Type: Journal Article)