Abstract | OBJECTIVES: Some ameloblastomas presumably originate from odontogenic epithelium within the connective tissue of dental follicles and dentigerous cysts. Therefore, it would seem reasonable to discuss as whether odontogenic epithelium proliferations, frankly displaying ameloblastomatous features ("focal ameloblastoma"), should be considered as an "early" ameloblastoma. STUDY DESIGN: Histopathological reports from 164 dental follicles and dentigerous cysts from the Department of Oral and Maxillofacial Surgery/ Oral Pathology of the VU Free University medical center in Amsterdam, The Netherlands, were reviewed. Histopathological slides from 39 cases reporting the presence of odontogenic epithelium within the connective tissue were re-evaluated in order to assess the possible presence of focal ameloblastomas. RESULTS: Focal ameloblastomas were detected in one dental follicle and in two dentigerous cysts. During a follow-up period of 6, 8 and 22 years, respectively, no clinical signs of (recurrent) ameloblastoma have occurred in these patients. CONCLUSIONS:
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Authors | Marco Meleti, Isaäc van der Waal |
Journal | Medicina oral, patologia oral y cirugia bucal
(Med Oral Patol Oral Cir Bucal)
Vol. 18
Issue 1
Pg. e60-4
(Jan 01 2013)
ISSN: 1698-6946 [Electronic] Spain |
PMID | 23085710
(Publication Type: Journal Article)
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Topics |
- Ameloblastoma
(pathology)
- Connective Tissue
(pathology)
- Dental Sac
(pathology)
- Dentigerous Cyst
(pathology)
- Epithelium
(pathology)
- Female
- Humans
- Male
- Young Adult
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