HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Effective radiotherapy cured cauda equina syndrome caused by remitted intracranial germinoma depositing.

Abstract
Cauda equina syndrome (CES) in children is very rare and can permanently disable. A remitted intracranial germinoma depositing on the spinal cord, leading to CES, has never been reported. We discuss the case of a 10-year-old girl who presented with sudden ataxia, low back pain, sensory deficits of the left lower extremity, and difficulty urinating and defecating 7 months after totally remitted intracranial germinoma postintracranial surgery and cranial irradiation. Magnetic resonance imaging (MRI) of the brain and spine showed multiple intradural extramedullary homogeneous masses from the cervical to lumbar levels, compressing the conus medullaris and cauda equina. After emergent craniospinal irradiation, the patient's neurologic symptoms dramatically subsided. A remitted intracranial germinoma depositing on her spinal cord could be the cause of CES. Early identification and a proper craniospinal irradiation may halt the progression of symptoms.
AuthorsYing-Chun Lu, Hueng-Chuen Fan, Hong-Wei Gao, Chang-Ming Chen, Yee-Min Jen, Shin-Nan Cheng, Shyi-Jou Chen
JournalPediatrics and neonatology (Pediatr Neonatol) Vol. 53 Issue 5 Pg. 315-9 (Oct 2012) ISSN: 2212-1692 [Electronic] Singapore
PMID23084725 (Publication Type: Case Reports, Journal Article, Review)
CopyrightCopyright © 2012. Published by Elsevier B.V.
Topics
  • Biopsy, Needle
  • Brain Neoplasms (pathology, radiotherapy, surgery)
  • Child
  • Female
  • Follow-Up Studies
  • Germinoma (pathology, radiotherapy, secondary, surgery)
  • Humans
  • Immunohistochemistry
  • Low Back Pain (diagnosis, etiology)
  • Magnetic Resonance Imaging (methods)
  • Polyradiculopathy (etiology, pathology, radiotherapy)
  • Rare Diseases
  • Risk Assessment
  • Spinal Neoplasms (pathology, radiotherapy, secondary)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: