Intravenous iron given prior to pregnancy for restless legs syndrome is associated with remission of symptoms.

Abstract

Restless legs syndrome (RLS) is more common during pregnancy than in the general population, occurring at a 2-3 times higher prevalence. While iron, genetics, and central nervous system dopamine have been shown to play major roles in RLS unrelated to pregnancy, the etiology and treatment of RLS during pregnancy have not been adequately delineated. We describe a novel approach where a 23-year-old female was given intravenous iron prior to pregnancy, with complete remission of RLS symptoms until five months postpartum. Factors other than iron status that may have influenced the course of remission and relapse were oral contraceptive use, antidepressant use, and a strong family history of RLS.

• Authors: Daniel L Picchietti, Victor C Wang, Matthew A Picchietti
• Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine (J Clin Sleep Med) Vol. 8 Issue 5 Pg. 585-6 (Oct 15 2012) ISSN: 1550-9397 [Electronic] United States
• PMID: 23066374 (Publication Type: Case Reports, Journal Article)

Chemical References

• Ferritins
• Iron

Topics

• Female
• Ferritins (blood)
• Humans
• Iron (administration & dosage, therapeutic use)
• Pregnancy
• Pregnancy Complications (drug therapy)
• Remission Induction
• Restless Legs Syndrome (complications, drug therapy)
• Young Adult