Abstract | PURPOSE: MATERIALS AND METHODS: We retrospectively evaluated 11 patients with 11 FNHs. Both gadoxetic acid- and SPIO-enhanced MR imaging were performed. A 3-dimensional (3D) volumetric interpolated breath-hold examination was used with the gadoxetic acid dynamic study. SPIO-enhanced MR imaging included T₂- and T₂*-weighted images. We quantitatively and qualitatively compared lesion-specific enhancement of both contrast media. RESULTS: The mean signal-to-noise (S/N) ratio of the FNH lesions differed significantly on pre- and postenhanced imaging of each contrast medium (P<0.05); mean contrast-to-noise (C/N) ratio did not (P>0.05). All observers described all lesions as hyperintense in the arterial phase on gadoxetic acid-enhanced MR imaging and observed the presence of central scar, fibrous septa, and rim most clearly in gadoxetic acid-enhanced hepatobiliary phase images. CONCLUSION:
Gadoxetic acid-enhanced MR imaging was more useful than SPIO-enhanced MR imaging in characterizing FNH.
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Authors | Kazuhiro Saito, Nobutaka Yoshimura, Toru Saguchi, Jinho Park, Katsutoshi Sugimoto, Soichi Akata, Fuminori Moriyasu, Koichi Tokuuye |
Journal | Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
(Magn Reson Med Sci)
Vol. 11
Issue 3
Pg. 163-9
( 2012)
ISSN: 1880-2206 [Electronic] Japan |
PMID | 23037560
(Publication Type: Comparative Study, Evaluation Study, Journal Article)
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Chemical References |
- Contrast Media
- Dextrans
- Magnetite Nanoparticles
- ferumoxtran-10
- gadolinium ethoxybenzyl DTPA
- Gadolinium DTPA
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Topics |
- Adult
- Aged
- Contrast Media
- Dextrans
- Female
- Focal Nodular Hyperplasia
(pathology)
- Gadolinium DTPA
- Humans
- Magnetic Resonance Imaging
(methods)
- Magnetite Nanoparticles
- Male
- Middle Aged
- Reproducibility of Results
- Retrospective Studies
- Sensitivity and Specificity
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