Abstract | BACKGROUND:
Chemotherapy based on repeated doses of praziquantel is still the most effective control strategy against Schistosomiasis, however artemisinin derivatives emerged as a family of compounds with schistomicide activity. The aim of the present work is to compare the efficacy of artemisinin-based therapies in the treatment and prophylaxis of human schistosomiasis. The design of this work involved a quantitative systematic review and meta-analysis. METHODOLOGY/PRINCIPAL FINDINGS: CONCLUSIONS/SIGNIFICANCE:
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Authors | Luis Pérez del Villar, Francisco J Burguillo, Julio López-Abán, Antonio Muro |
Journal | PloS one
(PLoS One)
Vol. 7
Issue 9
Pg. e45867
( 2012)
ISSN: 1932-6203 [Electronic] United States |
PMID | 23029285
(Publication Type: Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't, Review, Systematic Review)
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Chemical References |
- Antiprotozoal Agents
- Artemisinins
- Drug Combinations
- fanasil, pyrimethamine drug combination
- Praziquantel
- Sulfadoxine
- artemisinin
- Pyrimethamine
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Topics |
- Antiprotozoal Agents
(therapeutic use)
- Artemisinins
(adverse effects, therapeutic use)
- Clinical Trials as Topic
- Drug Combinations
- Drug Therapy, Combination
- Humans
- Praziquantel
(therapeutic use)
- Pyrimethamine
(therapeutic use)
- Schistosomiasis
(drug therapy, prevention & control)
- Sulfadoxine
(therapeutic use)
- Treatment Outcome
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