Abstract | INTRODUCTION: MATERIALS AND METHODS:
Zinc and copper concentration and Cu/Zn ratio in two 36-sample series of bladder cancer tissue and sera from patients with this neoplasm were matched with those of the control group. The amount of trace elements in every tissue sample was determined using atomic absorption spectrometry. This was correlated with tumor stage. RESULTS: While the copper concentrations reached statistically higher values in the bladder cancer tissue, the zinc levels in the sera and bladder tissue of the patients with this carcinoma were substantially lower as compared to those of the control group. The serum Cu/Zn ratio was significantly higher in the bladder cancer group and this increase was greater in the patients with muscle-invasive neoplasm. CONCLUSIONS:
|
Authors | Tomasz Golabek, Barbara Darewicz, Maria Borawska, Katarzyna Socha, Renata Markiewicz, Jacek Kudelski |
Journal | Urologia internationalis
(Urol Int)
Vol. 89
Issue 3
Pg. 342-7
( 2012)
ISSN: 1423-0399 [Electronic] Switzerland |
PMID | 23006800
(Publication Type: Journal Article)
|
Copyright | Copyright © 2012 S. Karger AG, Basel. |
Chemical References |
- Trace Elements
- Copper
- Zinc
|
Topics |
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Transitional Cell
(blood)
- Copper
(blood)
- Female
- Humans
- Male
- Middle Aged
- Spectrophotometry, Atomic
(methods)
- Trace Elements
- Urinary Bladder Neoplasms
(blood)
- Zinc
(blood)
|