Abstract | OBJECTIVE: To evaluate the perinatal outcomes in hydropic fetuses with congenital microcystic pulmonary lesions that underwent percutaneous, invasive, laser therapy. METHOD: This retrospective study reviews the literature and our experience between 2004 and 2010. Characteristics of the cystic lung lesions, liquor volume (presence of polyhydramnios or not), localization of ablation (vascular vs interstitial) and gestational age at which the procedure was performed were related to outcome (survival). RESULTS: In total, 16 fetuses with congenital lung lesions underwent 'invasive' percutaneous laser ablation, seven performed in our center and nine published cases. Survival rate was higher in fetuses with a subsequent postnatal diagnosis of bronchopulmonary sequestration (87.5%) compared with congenital adenomatoid malformation (28.6%; p = 0.04). The technique of vascular ablation was more successful (100%) than interstitial ablation (25.0%, p < 0.01). CONCLUSION:
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Authors | Rodrigo Ruano, Marcos Marques da Silva, Eugenia Maria Assunção Salustiano, Mark David Kilby, Uenis Tannuri, Marcelo Zugaib |
Journal | Prenatal diagnosis
(Prenat Diagn)
Vol. 32
Issue 12
Pg. 1127-32
(Dec 2012)
ISSN: 1097-0223 [Electronic] England |
PMID | 22990987
(Publication Type: Evaluation Study, Journal Article, Review)
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Copyright | © 2012 John Wiley & Sons, Ltd. |
Topics |
- Adult
- Bronchopulmonary Sequestration
(diagnostic imaging, surgery)
- Cohort Studies
- Cystic Adenomatoid Malformation of Lung, Congenital
(diagnostic imaging, surgery)
- Female
- Fetoscopy
(methods)
- Humans
- Hydrops Fetalis
(diagnostic imaging, surgery)
- Infant, Newborn
- Laser Therapy
(methods)
- Models, Biological
- Pregnancy
- Retrospective Studies
- Ultrasonography, Interventional
(methods)
- Ultrasonography, Prenatal
(methods)
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