Postoperative meningitis and epidural abscess due to extended-spectrum β-lactamase-producing Klebsiella pneumoniae: a case report and a review of the literature.

Abstract

17-year-old man had been involved in a traffic accident. He underwent a bilateral craniotomy with artificial dura mater to remove bilateral acute subdural hematomas. Seven months later, a right cranioplasty was performed using frozen auto-bone, and he developed extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae meningitis and an epidural abscess. Since his general status was poor, we could not remove the foreign body (artificial dura mater). He was successfully treated with meropenem and chronic suppression with oral trimethoprim-sulfamethoxazole. By describing this case and the results of a review of the pertinent literature, we discuss the importance of ESBL-producing Klebsiella pneumoniae meningitis in posttraumatic/postoperative patients.

• Authors: Kenichiro Yaita, Masanari Komatsu, Yusuke Oshiro, Yukihiro Yamaguchi
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 51 Issue 18 Pg. 2645-8 ( 2012) ISSN: 1349-7235 [Electronic] Japan
• PMID: 22989843 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Anti-Bacterial Agents
• Thienamycins
• Trimethoprim, Sulfamethoxazole Drug Combination
• beta-Lactamases
• Meropenem

Topics

• Adolescent
• Anti-Bacterial Agents (therapeutic use)
• Craniotomy (adverse effects)
• Drug Therapy, Combination
• Epidural Abscess (diagnosis, microbiology)
• Hematoma, Subdural, Acute (surgery)
• Humans
• Klebsiella Infections (complications, metabolism)
• Klebsiella pneumoniae (metabolism)
• Male
• Meningitis (diagnosis, microbiology)
• Meropenem
• Postoperative Period
• Thienamycins (therapeutic use)
• Treatment Outcome
• Trimethoprim, Sulfamethoxazole Drug Combination (therapeutic use)
• beta-Lactamases (metabolism)