HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Successful treatment of reactive hypoglycemia secondary to late dumping syndrome using miglitol.

Abstract
We herein describe a 59-year-old woman who had undergone a total gastrectomy for gastric carcinoma and suffered from postprandial hypoglycemia characterized by a loss of consciousness and spasms. She was diagnosed with reactive hypoglycemia and treated with nutrition therapy, but the frequency and severity of the hypoglycemic episodes did not decrease. She was subsequently treated successfully with miglitol, an alpha-glucosidase inhibitor (α-GI) taken twice a day; other α-GIs (acarbose and voglibose) were not effective. In conclusion, the administration of miglitol was effective for preventing reactive hypoglycemia secondary to late dumping syndrome.
AuthorsYukari Fujita, Daisuke Tamada, Junji Kozawa, Yoko Kobayashi, Shugo Sasaki, Tetsuhiro Kitamura, Tetsuyuki Yasuda, Norikazu Maeda, Michio Otsuki, Kohei Okita, Hiromi Iwahashi, Hideaki Kaneto, Tohru Funahashi, Akihisa Imagawa, Iichiro Shimomura
JournalInternal medicine (Tokyo, Japan) (Intern Med) Vol. 51 Issue 18 Pg. 2581-5 ( 2012) ISSN: 1349-7235 [Electronic] Japan
PMID22989830 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Enzyme Inhibitors
  • Glycoside Hydrolase Inhibitors
  • miglitol
  • 1-Deoxynojirimycin
Topics
  • 1-Deoxynojirimycin (analogs & derivatives, therapeutic use)
  • Dose-Response Relationship, Drug
  • Dumping Syndrome (complications)
  • Enzyme Inhibitors (therapeutic use)
  • Female
  • Glycoside Hydrolase Inhibitors
  • Humans
  • Hypoglycemia (drug therapy, etiology)
  • Middle Aged
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: