Protective effect of transplantation of neonatal liver cell nuclei on the model of acute toxic hepatitis.

Abstract	We present the results of comparative analysis of functional and morphological changes in the liver of animals with experimental CCl(4)-induced hepatitis under conditions of transplantation of neonatal liver cells and nuclei. It was found that transplantation of neonatal liver cell nuclei in acute toxic hepatitis provides better functional and structural state of the target organ.
Authors	A A Runovich, Yu I Pivovarov, T E Kuril'skaya, A S Sergeeva, I V Babushkina, S L Bogorodskaya
Journal	Bulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 153 Issue 4 Pg. 563-8 (Aug 2012) ISSN: 1573-8221 [Electronic] United States
PMID	22977871 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Carbon Tetrachloride L-Lactate Dehydrogenase Aspartate Aminotransferases Alanine Transaminase
Topics	Alanine Transaminase (metabolism) Animals Aspartate Aminotransferases (metabolism) Carbon Tetrachloride (toxicity) Chemical and Drug Induced Liver Injury (therapy) Disease Models, Animal Hepatocytes (transplantation) L-Lactate Dehydrogenase (metabolism) Liver (enzymology, pathology) Male Nuclear Transfer Techniques Rats Statistics, Nonparametric Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!