Association of body mass index with removal of etonogestrel subdermal implant.

Abstract

BACKGROUND:

Bleeding irregularities represent the most common etonogestrel subdermal implant (ESI) removal indication.

STUDY DESIGN:

ESI placements (n=304) from June 2007 to April 2011 were grouped by removal indications. Group characteristics were compared using one-way analysis of variance, Kruskal-Wallis and χ(2) test.

RESULTS:

Of 304 insertions, 30.6% reported irregular bleeding. Removal indications included bleeding (Group 1, n=50), side effects (Group 2, n=17) and desired pregnancy/no need (Group 3, n=25). Group 4 kept (n=198) or reinserted (n=14) ESI. Median body mass index was lower for Group 1 compared to other groups (p=.012). Group 3 was older than Group 1 or 4 (p=.021), and more likely parous (p<.001) and postpartum (p=.001) than other groups. Lactational placement was more common in Group 3 than 4 (p<.001). Obese women were 2.6 times less likely to remove ESI for bleeding vs. normal-weight or overweight women (95% confidence interval, 1.2-5.7; p=.014).

CONCLUSIONS:

After adjusting for age and parity, obese women were less likely to have ESI removal for bleeding.

• Authors: Petra M Casey, Margaret E Long, Mary L Marnach, Jennifer Fleming-Harvey, Linda B Drozdowicz, Amy L Weaver
• Journal: Contraception (Contraception) Vol. 87 Issue 3 Pg. 370-4 (Mar 2013) ISSN: 1879-0518 [Electronic] United States
• PMID: 22959901 (Publication Type: Journal Article)
• Copyright: Copyright © 2013 Elsevier Inc. All rights reserved.

Chemical References

• Contraceptive Agents, Female
• etonogestrel
• Desogestrel

Topics

• Adolescent
• Adult
• Body Mass Index
• Contraceptive Agents, Female (administration & dosage, adverse effects)
• Desogestrel (administration & dosage, adverse effects)
• Device Removal (statistics & numerical data)
• Female
• Humans
• Menstruation Disturbances (chemically induced)
• Middle Aged
• Retrospective Studies
• Uterine Hemorrhage (chemically induced)
• Young Adult