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[Palindromic rheumatism].

Abstract
Palindromic rheumatism is characterized by episodes of arthritis or para-arthritis leaving no residual or radiographic changes. Several diseases should be ruled out in the differential diagnosis. Evolution to rheumatoid arthritis is common, especially in patient with positive rheumatoid factor and anticitrullinated peptides. In seronegative patients, palindromic rheumatism could be part of the spectrum of autoinflammatory diseases because of a high frequency of MEFV mutations. Treatment remains discussed. The use of antimalarials could delay the development of rheumatoid arthritis or another connective tissue disease.
AuthorsM Vayssade, Z Tatar, M Soubrier
JournalLa Revue de medecine interne (Rev Med Interne) Vol. 34 Issue 1 Pg. 47-52 (Jan 2013) ISSN: 1768-3122 [Electronic] France
Vernacular TitleRhumatisme palindromique.
PMID22939655 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2012. Published by Elsevier SAS.
Chemical References
  • Cytoskeletal Proteins
  • MEFV protein, human
  • Pyrin
  • Citrulline
  • Rheumatoid Factor
Topics
  • Arthritis (diagnosis)
  • Arthritis, Rheumatoid (physiopathology)
  • Citrulline (analysis)
  • Cytoskeletal Proteins (genetics)
  • Diagnosis, Differential
  • Disease Progression
  • Hereditary Autoinflammatory Diseases (diagnosis)
  • Humans
  • Mutation (genetics)
  • Pyrin
  • Rheumatic Diseases (diagnosis, genetics, physiopathology)
  • Rheumatoid Factor (analysis)

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