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Presence of Helicobacter pylori in patients with non-ulcer dyspepsia revealing normal antral histological characteristics.

Abstract
Two hundred consecutive patients suffering from non-ulcer dyspepsia were studied for the presence of Helicobacter pylori in antral gastritis and normal antral mucosa, using the combination of culture, modified Giemsa stain and a sensitive immunoperoxidase stain as means of detection. H. pylori gastritis was present in 56% of the cases. The bacterium was present in 75% of cases of normal antral mucosa, however, in low numbers. It is concluded that 87% of patients with non-ulcer dyspepsia are H. polory-positive implying a larger role for the micro-organism as initially thought.
AuthorsR J Loffeld, E Stobberingh, J A Flendrig, J W Arends
JournalDigestion (Digestion) Vol. 47 Issue 1 Pg. 29-34 ( 1990) ISSN: 0012-2823 [Print] Switzerland
PMID2292346 (Publication Type: Journal Article)
Topics
  • Biopsy
  • Dyspepsia (microbiology)
  • Female
  • Gastric Mucosa (microbiology)
  • Gastritis (microbiology, pathology)
  • Helicobacter Infections (diagnosis)
  • Helicobacter pylori (isolation & purification)
  • Humans
  • Immunoenzyme Techniques
  • Male
  • Middle Aged

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