Very late-onset corneal scar triggered by trauma after photorefractive keratectomy.

A 54-year-old woman who had photorefractive keratectomy (PRK) more than 10 years earlier presented with a history of being hit in the eye by a tree branch and developing blurred vision a short time later. The corrected visual acuity was 20/100 with localized grade 3 stromal haze. The haze intensified despite initial response to corticosteroids and cyclosporine, and treatment with phototherapeutic keratectomy and 0.02% mitomycin-C (MMC) was effective in restoring corneal clarity and normal vision. Late-onset stromal scar can be triggered by trauma years after PRK. Phototherapeutic keratectomy with MMC can be an effective treatment for late-onset scar. Persistent haze or scar after trauma if PRK had not been performed previously is exceedingly rare.
AuthorsBeatriz A F Gomes, David Smadja, Edgar M Espana, Eric S Ahn, Marcelo V Netto, Marcony R Santhiago
JournalJournal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 38 Issue 9 Pg. 1694-7 (Sep 2012) ISSN: 1873-4502 [Electronic] United States
PMID22906452 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
Chemical References
  • Alkylating Agents
  • Glucocorticoids
  • Mitomycin
  • Alkylating Agents (administration & dosage)
  • Cornea (physiopathology, surgery)
  • Corneal Injuries
  • Corneal Opacity (etiology, physiopathology, surgery)
  • Eye Injuries (etiology, physiopathology, surgery)
  • Female
  • Glucocorticoids (therapeutic use)
  • Humans
  • Lasers, Excimer
  • Middle Aged
  • Mitomycin (administration & dosage)
  • Myopia (surgery)
  • Photorefractive Keratectomy
  • Postoperative Complications
  • Visual Acuity (physiology)
  • Wounds, Nonpenetrating (etiology, physiopathology, surgery)

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