Antiangiogenic therapy in the management of breast cancer.

Abstract

An improved understanding of the important role of angiogenesis in tumor biology has led to development of different antiangiogenic therapies. Numerous clinical studies for several antiangiogenic agents have recently been conducted in breast cancer patients and have shown clinically significant improvement in outcomes. This review focuses on current progress in the field of antiangiogenic therapy in the management of breast cancer, also highlighting issues regarding future therapeutic development that result in the greatest clinical benefits and minimizing the adverse effects.

• Authors: Yuan Wu, Wei-li Sun, Ji-feng Feng
• Journal: Asia-Pacific journal of clinical oncology (Asia Pac J Clin Oncol) Vol. 9 Issue 2 Pg. 110-6 (Jun 2013) ISSN: 1743-7563 [Electronic] Australia
• PMID: 22898270 (Publication Type: Journal Article, Review)
• Copyright: © 2012 Wiley Publishing Asia Pty Ltd.

Chemical References

• Angiogenesis Inhibitors

Topics

• Angiogenesis Inhibitors (therapeutic use)
• Breast Neoplasms (blood supply, drug therapy)
• Disease Management
• Female
• Humans
• Neovascularization, Pathologic (drug therapy)