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Landiolol for junctional ectopic tachycardia refractory to amiodarone after pediatric cardiac surgery.

Abstract
Postoperative junctional ectopic tachycardia (JET) in children undergoing cardiac surgery is a serious arrhythmia that is associated with considerable morbidity and mortality. We present here a case of successful landiolol therapy for postoperative JET in a 3-month-old infant who underwent ventricular septal defect closure and right pulmonary artery plasty. His left ventricular function was poor postoperatively. The JET was refractory to amiodarone and caused severe hypotension, which was required cardiac massage. Continuous intravenous infusion of low-dose landiolol reduced the persistent JET rate immediately, and restored to sinus rhythm with stable hemodynamics.
AuthorsTomomi Hasegawa, Yoshihiro Oshima, Ayako Maruo, Hironori Matsuhisa, Tasuku Kadowaki, Rei Noda
JournalGeneral thoracic and cardiovascular surgery (Gen Thorac Cardiovasc Surg) Vol. 61 Issue 6 Pg. 350-2 (Jun 2013) ISSN: 1863-6713 [Electronic] Japan
PMID22893321 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Arrhythmia Agents
  • Morpholines
  • landiolol
  • Urea
  • Amiodarone
Topics
  • Amiodarone (therapeutic use)
  • Anti-Arrhythmia Agents (therapeutic use)
  • Cardiac Surgical Procedures (adverse effects)
  • Constriction, Pathologic
  • Heart Septal Defects, Ventricular (surgery)
  • Humans
  • Infant
  • Male
  • Morpholines (therapeutic use)
  • Pulmonary Artery (abnormalities, surgery)
  • Tachycardia, Ectopic Junctional (drug therapy, etiology)
  • Urea (analogs & derivatives, therapeutic use)

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