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Focal parietal necrosis of the sigmoid due to atypical neuroleptics: a case report.

Abstract
We present the case of a 26-year-old man with schizoid personality disorder who suffered from a very focal and transparietal necrosis of the sigmoid after an overdose of atypical neuroleptics. This is a singular, rather unknown and potentially lethal side effect of these drugs. The physiopathology of this complication is multifactorial.
AuthorsArnaud Devresse, Philippe Maldague, Bruno Coulier, Frédéric Pierard, Isabelle Gielen
JournalActa gastro-enterologica Belgica (Acta Gastroenterol Belg) Vol. 75 Issue 2 Pg. 263-5 (Jun 2012) ISSN: 1784-3227 [Print] Belgium
PMID22870793 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Anxiety Agents
  • Anticonvulsants
  • Antidepressive Agents
  • Antipsychotic Agents
  • Dibenzothiazepines
  • Triazines
  • Citalopram
  • Quetiapine Fumarate
  • Clopenthixol
  • Lorazepam
  • Lamotrigine
  • Trazodone
  • clothiapine
Topics
  • Adult
  • Anti-Anxiety Agents (poisoning)
  • Anticonvulsants (poisoning)
  • Antidepressive Agents (poisoning)
  • Antipsychotic Agents (poisoning)
  • Citalopram (poisoning)
  • Clopenthixol (poisoning)
  • Dibenzothiazepines (poisoning)
  • Drug Overdose (complications)
  • Enterocolitis, Necrotizing (chemically induced, surgery)
  • Humans
  • Lamotrigine
  • Lorazepam (poisoning)
  • Male
  • Quetiapine Fumarate
  • Schizoid Personality Disorder (drug therapy)
  • Trazodone (poisoning)
  • Triazines (poisoning)

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