Emotional-type psychopathologic symptoms among patients with terminal chronic alcohol-induced liver cirrhosis.

Abstract

INTRODUCTION:

Patients with toxic substance abuse syndrome, such as alcohol abuse, have elevated psychopathologic morbidity and mortality such as mood disorders.

OBJECTIVE:

To evaluate the emotional-type psychopathologic symptoms in patients with alcohol-induced hepatic cirrhosis on the liver transplant waiting list.

MATERIALS AND METHODS:

Patients with alcoholic liver cirrhosis who were candidates for liver transplant (n = 41) completed the SA-45 questionnaire (González y Cuevas; 88), which assesses nine dimensions: somatizations, obsessive-compulsivity, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, and psychoticism. A control group consisted of patients with chronic nonalcoholic terminal hepatopathies (n = 22).

RESULTS:

Seventy-six percent of patients had some kind of psychopathologic symptom compared to 68% of the patients in the control group with other nonalcoholic etiologies (P > .05). The emotional-type clinical symptoms were: (1) somatizations: 37% of patients with alcoholic cirrhosis had this type of clinical symptoms compared to 32% of the control group (P > .05); (2) obsessive-compulsivity: 56% versus 46%, respectively (P > .05); (3) interpersonal sensitivity: 19% versus 9%, respectively (P > .05); (4) depression: 54% versus 27%, respectively (P = .045); (5) anxiety: 59% versus 46%, respectively (P > .05); (6) hostility: 29% versus 5%, respectively (P = .021); (7) phobic anxiety: 10% versus 14%, respectively (P > .05); (8) paranoid Ideation: 7% versus 5%, respectively (P > .05); (9) psychoticism: 5% versus 4%, respectively (P > .05).

CONCLUSIONS:

The patients with alcoholic liver cirrhosis on the liver transplant waiting list had elevated psychopathologic symptoms. Depressive- and hostile-type emotional alterations were most frequent in this type of patients.

• Authors: A López-Navas, A Ríos, F J Moya-Faz, B Febrero, M I Jiménez-Morales, F J Orteso, A Ros-Martínez, L Martínez-Alarcón, J A Pons, M Miras, P Ramírez, P Parrilla
• Journal: Transplantation proceedings (Transplant Proc) 2012 Jul-Aug Vol. 44 Issue 6 Pg. 1510-2 ISSN: 1873-2623 [Electronic] United States
• PMID: 22841199 (Publication Type: Journal Article)
• Copyright: Copyright © 2012. Published by Elsevier Inc.

Topics

• Case-Control Studies
• Chi-Square Distribution
• Depression (epidemiology, psychology)
• Emotions
• Hostility
• Humans
• Liver Cirrhosis, Alcoholic (epidemiology, psychology, surgery)
• Liver Transplantation
• Mental Disorders (diagnosis, epidemiology, psychology)
• Multivariate Analysis
• Odds Ratio
• Spain (epidemiology)
• Waiting Lists