Hypertrophic donavanosis in a young pregnant woman.

Abstract

BACKGROUND:

Donovanosis is a chronic bacterial illness, progressive and indolent, which normally attacks the skin and mucous membranes in the genital and perigenital regions.

CASE:

An 18-year-old pregnant female presented with large, hypertrophic lesions in the ano-genital region. HIV serology was negative. Pap smear revealed a CIN 1 associated with HPV infection. Biopsy yielded macrophages laden with Gram-negative Donovan bodies.

SUMMARY AND CONCLUSION:

A diagnosis of vulvar and perianal donovanosis was reached; the patient decided to terminate the pregnancy and was treated with azithromycin, which led to clinical resolution.

• Authors: C A Liverani, D Lattuada, S Mangano, C Pignatari, D Puglia, E Monti, G Bolis
• Journal: Journal of pediatric and adolescent gynecology (J Pediatr Adolesc Gynecol) Vol. 25 Issue 4 Pg. e81-3 (Aug 2012) ISSN: 1873-4332 [Electronic] United States
• PMID: 22840941 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2012 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

Topics

• Abortion, Induced
• Adolescent
• Anus Diseases (microbiology)
• Female
• Granuloma Inguinale (diagnosis)
• Humans
• Pregnancy
• Pregnancy Complications, Infectious (diagnosis)
• Vulvar Diseases (microbiology)