Abstract | OBJECTIVE: METHODS: The medical records of 56 patients who were treated for metastatic testicular tumors by chemotherapy at a single institute between 2002 and 2010 were retrospectively reviewed. RESULTS: Among 56 patients, 12 patients needed ureteral stenting before chemotherapy. The proportion of patients requiring ureteral stenting was significantly higher in seminoma than non- seminoma (47 and 12%, respectively, P < 0.05). The ureteral stent was removed after chemotherapy or retroperitoneal lymph node dissection in all patients, except for one patient who died of cancer during chemotherapy. At retroperitoneal lymph node dissection, ureters were spared in three patients, a partial ureterectomy was needed in one patient, and no case underwent adjunctive nephrectomy. These 11 patients presented no local and distant recurrence at median follow-up of 44 months. Ureteral stenting increased the estimated glomerular filtration rate to more than 60 ml/min before chemotherapy in all patients, but it decreased to <60 ml/min in 6 of 11 patients after chemotherapy. CONCLUSIONS:
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Authors | Atsushi Ikeda, Koji Kawai, Satoshi Ando, Takehiro Oikawa, Hiromu Inai, Tomokazu Kimura, Ei-ichiro Takaoka, Takayuki Yoshino, Takahiro Suetomi, Takahiro Kojima, Jun Miyazaki, Hiroyuki Nishiyama |
Journal | Japanese journal of clinical oncology
(Jpn J Clin Oncol)
Vol. 42
Issue 8
Pg. 748-52
(Aug 2012)
ISSN: 1465-3621 [Electronic] England |
PMID | 22782964
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Antineoplastic Agents
(therapeutic use)
- Female
- Germinoma
(complications)
- Humans
- Kidney
(physiopathology)
- Lymph Node Excision
- Lymphatic Metastasis
- Male
- Middle Aged
- Nephrectomy
- Retroperitoneal Space
- Retrospective Studies
- Seminoma
(complications)
- Stents
- Testicular Neoplasms
(complications, drug therapy, pathology)
- Ureteral Obstruction
(etiology, physiopathology, therapy)
- Young Adult
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