Serious
Cystadenoma (SCA) of the Pancreas is seldom malignant and is usually monitored over time. Here we report a case of SCA an enlarged
cyst that had to be excised because it was difficult to diagnose by intraductal papillary-
mucinous neoplasm (IPMN). The patient was a 58-year-old woman with
thecoma of the right ovary accompanied by
Meigs syndrome, who had undergone abdominal total
hysterectomy and bilateral
oophorectomy. Abdominal computed tomography scan (CT) showed a multilocular
cyst 2.4 cm in diameter in the head of the pancreas. Fourteen months later, a periodic CT showed that the multilocular
cyst had enlarged from 2.4 to 3.5 cm in diameter. Branch duct intraductal papillary-
mucinous neoplasm (IPMN) with a tendency to enlargement and with mural nodule was suspected. Pylorus-preserving
pancreatoduodenectomy (PPPD) was performed, and pathological findings revealed that the
cyst was lined with a single layer of simple cuboidal epithelium.
Periodic acid-Shiff staining, with and without
diastase digestion, showed abundant
glycogen within epithelial cells, yielding a definitive diagnosis of SCA. The
ascites were probably due to the
Meigs syndrome pressing the
cyst, and the size of the
cyst appeared smaller than the real size.