Serum levels of 25-hydroxy-vitamin D3 among sun-protected outdoor workers in Israel.

Abstract

The objective of this study was to evaluate the effect of reduced sun exposure of outdoor workers on vitamin D status using different modalities of sun protection, for primary prevention of skin cancer. 25-OH-D3 measurements were performed in two successive winters, 8 (interim) and 20 months after initiation of the study, in three groups of male outdoor workers, enrolled in either a complete, partial or minimal sun protection program. Ambient solar UVB radiation was monitored simultaneously. No intragroup or intergroup differences were observed between the interim- and postintervention measurements of mean 25-OH-D3, which were close to 30 ng mL(-1). Significant risk factors for postintervention 25-OH-D3 levels >33.8 ng mL(-1) (a surrogate for reduced sun protection) were: previous sunburn episodes (OR 2.5; 95% CI 1.01-6.3; P=0.05) and younger age (OR 0.92; 95 CI 0.86-0.98; P=0.009). Outdoor workers of Western, compared with those of Eastern paternal origin had a borderline significant risk (OR 2.4; 95% CI 0.9-6.3; P=0.07). A borderline significant effect (OR 2.9; 95% CI 0.97-10.1; P=0.085) was also noted for those in the minimal intervention group. In conclusion, sun protection among outdoor workers following a successful intervention did not suppress mean winter 25-OH-D3.

• Authors: Esther Azizi, Felix Pavlotsky, Avraham Kudish, Pazit Flint, Arie Solomon, Yehuda Lerman, Bernice Oberman, Siegal Sadetzki
• Journal: Photochemistry and photobiology (Photochem Photobiol) 2012 Nov-Dec Vol. 88 Issue 6 Pg. 1507-12 ISSN: 1751-1097 [Electronic] United States
• PMID: 22762563 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2012 Wiley Periodicals, Inc. Photochemistry and Photobiology © 2012 The American Society of Photobiology.

Chemical References

• Sunscreening Agents
• Calcifediol

Topics

• Adult
• Aging
• Calcifediol (blood)
• Humans
• Israel
• Male
• Middle Aged
• Multivariate Analysis
• Occupational Exposure
• Odds Ratio
• Sunburn (prevention & control)
• Sunscreening Agents (administration & dosage, pharmacology)