In four groups of rabbits on model of a heavy alkaline
burn of a cornea and a limbus of various extent character and outcomes of healing of an eye surface as a result of early (it is direct after a
burn) applications is investigated: only
conservative treatment - group I,
conservative treatment + time blepharorrhaphy - group II,
conservative treatment + covering of a cornea and a limbus of amnionic membrane - group III, and also combinations of
conservative treatment, temporary of blepharorrhaphy and coverings of a cornea and a limbus amnionic membrane - group IV. In all groups
conservative treatment included: an instillation of
maxitrol within 14 days with transition to a mortgaging of Unguentum Tetracyclini of 1% 3 times a day. Depending on width of sector of the
burn measured in circular degrees, each group included 4 subgroups: 60° - a subgroup "A", 120° " " - 180° - "B", 270° "Γ" - (on 4 eyes in a subgroup). Results estimated daily within the first 10 days, and further every 5 days (during 3 months) after a
burn with photoregistration at colouring of an eye surface of 1% a
solution fluorescein-natrium. On the basis of the received results it is established that the early fortnight time blepharorrhaphy (as addition to
conservative treatment) is the most effective and accessible method (from considered) optimisation of healing of an eye surface at heavy
burns of eyes with capture to 75% of the area of a cornea and a limbus.