Abstract | OBJECTIVES: DESIGN: SETTING: University-affiliated teaching hospital. PARTICIPANTS: Eighty consecutive patients who suffered from recurrent anterior epistaxis presented to the Otolaryngology Department at the Eye and ENT Hospital, Fudan University between February 2011 and June 2011. MAIN OUTCOME MEASURES: The following outcome measures were assessed: bleeding intensity, bleeding frequency 4 and 12 weeks after treatment (0 = no bleeding, 1 = reduced bleeding, 2 = the same, 3 = worse), participant's perception of discomfort during the management (grade 0-10, where 10 is the worst pain) and complications. RESULTS: At 12 weeks, 85% of laser patients versus 40% of control patients had no reported bleeding. The outcome score at 4 weeks after treatment showed no significant difference between the two groups (P = 0.130, P > 0.05); however, the outcome score at 12 weeks after treatment showed a significant difference between the two groups (P = 0.000, P < 0.01). The median and mean ± sd pain levels experienced were 5.0 and 5.2 ± 2.2. Both groups had no complications. CONCLUSIONS: It can be concluded that Nd:YAG laser photocoagulation is a preferable therapy in the treatment of recurrent epistaxis, especially in terms of long-lasting efficacy. The level of pain associated with the procedure was tolerated. It is a simple, easy, safe and rapid therapy, which can be performed in an office setting.
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Authors | J Zhang, R Qiu |
Journal | Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
(Clin Otolaryngol)
Vol. 37
Issue 4
Pg. 271-5
(Aug 2012)
ISSN: 1749-4486 [Electronic] England |
PMID | 22672214
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | © 2012 Blackwell Publishing Ltd. |
Chemical References |
- Anti-Bacterial Agents
- Anti-Infective Agents, Local
- Drug Combinations
- Ointments
- Mineral Oil
- Neomycin
- Chlorhexidine
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Topics |
- Administration, Topical
- Adult
- Anti-Bacterial Agents
(therapeutic use)
- Anti-Infective Agents, Local
(therapeutic use)
- Chi-Square Distribution
- Chlorhexidine
(therapeutic use)
- Drug Combinations
- Epistaxis
(drug therapy, therapy)
- Female
- Humans
- Lasers, Solid-State
(therapeutic use)
- Light Coagulation
(methods)
- Male
- Mineral Oil
(therapeutic use)
- Neomycin
(therapeutic use)
- Ointments
- Pain Measurement
- Postoperative Complications
- Prospective Studies
- Recurrence
- Single-Blind Method
- Statistics, Nonparametric
- Surveys and Questionnaires
- Treatment Outcome
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