Abstract | BACKGROUND: OBJECTIVES: METHODS: This is a retrospective analysis of 1905 patients who underwent patch testing for allergic contact dermatitis. Associations were analyzed by χ testing. RESULTS: Of all patients, 9.5% reacted to quaternium-15, 7.2% reacted to formaldehyde, and 5.4% reacted to both (P < 0.001). Of 137, 86 had strong (2 or 3+) and 51 had weak (1+ or +/-) formaldehyde reactions; there was no relationship between the severity of formaldehyde reactivity and responsiveness to quaternium-15 (P = 0.229). Sex analysis did not change these findings. LIMITATIONS: This study is limited by its retrospective analysis and small sample size. CONCLUSIONS:
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Authors | Ashika Odhav, Donald V Belsito |
Journal | Dermatitis : contact, atopic, occupational, drug
(Dermatitis)
2012 Jan-Feb
Vol. 23
Issue 1
Pg. 39-43
ISSN: 2162-5220 [Electronic] United States |
PMID | 22653068
(Publication Type: Journal Article)
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Chemical References |
- Preservatives, Pharmaceutical
- Formaldehyde
- quaternium-15
- Methenamine
|
Topics |
- Chi-Square Distribution
- Dermatitis, Allergic Contact
(etiology)
- Female
- Formaldehyde
(adverse effects, chemistry)
- Humans
- Male
- Methenamine
(adverse effects, analogs & derivatives, chemistry)
- Patch Tests
(methods)
- Predictive Value of Tests
- Preservatives, Pharmaceutical
(adverse effects, chemistry)
- Retrospective Studies
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