A malignant granular cell tumor excised with mohs micrographic surgery.

Abstract

Malignant granular cell tumors are extremely rare, aggressive neoplasms displaying rapid growth and frequent associated metastatic disease. Excision and evaluation for metastatic disease are mandatory. We present a 54-year-old patient with a malignant granular cell tumor, treated with Mohs micrographic surgery. Cutaneous granular cell tumors are uncommon neoplasms, likely of perineural origin. Most follow a benign and uneventful course, with wide local excision being the treatment of choice (Enzinger, 1988). The malignant granular cell tumor is an extremely rare, aggressive variant, which provides a diagnostic challenge and management dilemma, especially with early presentation when it may be mistaken for other entities. There is also controversy regarding surgical management and follow-up of both benign and malignant granular cell tumors.

• Authors: David Crowe, Elias E Ayli, Hugh M Gloster Jr
• Journal: Case reports in oncological medicine (Case Rep Oncol Med) Vol. 2012 Pg. 453569 ( 2012) ISSN: 2090-6714 [Electronic] United States
• PMID: 22606454 (Publication Type: Case Reports)