Abstract | AIM: To evaluate the evidence on the impact of different debridement techniques on healing and their efficacy in the treatment of leg ulcers. METHODS: Web-based search (PubMed) for trials investigating surgical, enzymatic, autolytic, osmotic, ultrasound-assisted, and biosurgical wound debridement on leg ulcers with regard to healing and efficacy. RESULTS: Both surgical and hydrosurgical methods proved to be effective debridement techniques. For conventional surgical debridement, a significantly greater reduction of the wound surface area and a higher healing rate were reported. Studies on autolytic, osmotic, and enzymatic wound debridement showed effective debridement for krill enzymes, dextranomer and manuka honey. Only for manuka honey was there a significantly greater reduction of the wound surface area compared to standard treatment. One study comparing fibrinolysin/ DNAse with placebo and one comparing autolytic with enzymatic debridement showed no significant differences between the respective techniques. Trials on ultrasound-assisted wound debridement reported a positive impact on healing. A significant wound surface area reduction was demonstrated in one of them. Maggot therapy led to effective debridement. The largest trial showed no significantly improved healing. CONCLUSIONS:
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Authors | Martin Doerler, Stefanie Reich-Schupke, Peter Altmeyer, Markus Stücker |
Journal | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
(J Dtsch Dermatol Ges)
Vol. 10
Issue 9
Pg. 624-32
(Sep 2012)
ISSN: 1610-0387 [Electronic] Germany |
PMID | 22591415
(Publication Type: Editorial, Meta-Analysis, Review)
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Copyright | © The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin. |
Topics |
- Debridement
(statistics & numerical data)
- Dermatologic Surgical Procedures
(statistics & numerical data)
- Humans
- Leg Ulcer
(epidemiology, surgery)
- Postoperative Complications
(epidemiology, prevention & control)
- Prevalence
- Treatment Outcome
- Wound Healing
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