Abstract | PURPOSE: METHODS: RESULTS: SOD concentrations after delivery of 40 Gy/4 weeks was associated with the development of RP. The best predictive ability of SOD was observed for a cut-off value of 56 unit/ml, with a sensitivity of 0.80 (95% CI 0.28-0.99), and a specificity of 0.67 (95% CI 0.43-0.65) (p = 0.040). CONCLUSION: Serum SOD may be a potential predictor for RP, which need to be further verified.
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Authors | Dongqing Wang, Jingyu Zhu, Mingping Sun, Baosheng Li, Ling Wei, Zhongtang Wang, Hongfu Sun |
Journal | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
(Biomarkers)
Vol. 17
Issue 5
Pg. 455-62
(Aug 2012)
ISSN: 1366-5804 [Electronic] England |
PMID | 22590985
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antigens, Neoplasm
- Chemokine CCL3
- Interleukin-6
- Keratin-19
- Transforming Growth Factor beta1
- antigen CYFRA21.1
- Intercellular Adhesion Molecule-1
- Superoxide Dismutase
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Topics |
- Antigens, Neoplasm
(blood)
- Carcinoma, Non-Small-Cell Lung
(therapy)
- Chemokine CCL3
(blood)
- Chemoradiotherapy
(adverse effects)
- Enzyme-Linked Immunosorbent Assay
(methods)
- Female
- Humans
- Intercellular Adhesion Molecule-1
(blood)
- Interleukin-6
(blood)
- Keratin-19
(blood)
- Lung Neoplasms
(therapy)
- Male
- Middle Aged
- Predictive Value of Tests
- Prognosis
- Radiation Pneumonitis
(blood, diagnosis, etiology)
- Reproducibility of Results
- Sensitivity and Specificity
- Superoxide Dismutase
(blood)
- Time Factors
- Transforming Growth Factor beta1
(analysis)
- Treatment Outcome
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