Abstract | BACKGROUND: PATIENTS AND METHODS: We retrospectively analyzed the records of 37 histologically confirmed MLS patients who were treated at the University of Texas MD Anderson Cancer Center from January 2000 to December 2009 with doxorubicin 75-90 mg/m2 over 72 hours combined with ifosfamide 10 gm/m2 in the first-line setting. Response was assessed using RECIST and Choi criteria. The Kaplan-Meier method and log-rank test was used to estimate clinical outcomes. RESULTS: The median follow-up period was 50.1 months. The overall response rates were 43.2% using RECIST and 86.5% using the Choi criteria. The 5-year disease-free survival rate was 90% for patients with resectable tumors. Median time to progression and overall survival time for the advanced-disease group were 23 and 31.1 months, respectively. CONCLUSION:
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Authors | Daniela Katz, Piyaporn Boonsirikamchai, Haeson Choi, Alexander J Lazar, Wei-Lein Wang, Lianchun Xiao, Min S Park, Vinod Ravi, Robert S Benjamin, Dejka M Araujo |
Journal | Clinical sarcoma research
(Clin Sarcoma Res)
Vol. 2
Issue 1
Pg. 2
(Jan 24 2012)
ISSN: 2045-3329 [Electronic] England |
PMID | 22587772
(Publication Type: Journal Article)
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