Abstract | OBJECTIVE: We evaluated whether endotracheal tube (ETT) intracuff alkalinized lidocaine was superior to saline in blunting emergence coughing, postoperative sore throat, and hoarseness in smokers. METHODS: RESULTS: Intracuff alkalinized 2% lidocaine was superior to saline in blunting emergence coughing (p < 0.001). The incidence of sore throat was significantly lower in the L group at the post- anesthesia care unit (PACU) (p = 0.02). However, at 24 hours after extubation, sore throat incidence was similar in both groups (p = 0.07). Incidence of hoarseness was similar in both groups. Intracuff pressure in the saline group increased with time while the intracuff pressure in the lidocaine group remained constant. CONCLUSION: The present study demonstrated that the intracuff alkalinized 2% lidocaine was superior to saline in decreasing the incidence of emergence coughing and sore throat during the postoperative period in smokers.
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Authors | Laís Helena Camacho Navarro, Rodrigo Moreira e Lima, Andressa Simões Aguiar, José Reinaldo Cerqueira Braz, Jeffrey M Carness, Norma Sueli Pinheiro Módolo |
Journal | Revista da Associacao Medica Brasileira (1992)
(Rev Assoc Med Bras (1992))
2012 Mar-Apr
Vol. 58
Issue 2
Pg. 248-53
ISSN: 1806-9282 [Electronic] Brazil |
PMID | 22569622
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Sodium Chloride
- Lidocaine
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Topics |
- Anesthesia, General
(adverse effects)
- Cough
(etiology)
- Double-Blind Method
- Female
- Hoarseness
(etiology)
- Humans
- Incidence
- Intubation, Intratracheal
(methods)
- Lidocaine
(administration & dosage)
- Male
- Pharyngitis
(etiology)
- Postoperative Complications
- Smoking
- Sodium Chloride
(administration & dosage)
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