Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice.

Abstract

Ethanolic extract of rhizomes of Curcuma aromatica (Zingiberaceae) was investigated for its antitussive effect on Sulfur dioxide induced cough model in mice. The extract exhibited significant antitussive activity in a dose dependant manner. The activity was compared with the prototype antitussive agent codeine phosphate. The ethanolic extract at the dose of lOOmg. 200mg and 400mg/kg body weight, po, showed 68%, 74% and 79% of inhibition of cough with respect to control group.

• Authors: G D Marina, T R Prashith Kekuda, S J Sudarshan
• Journal: Ancient science of life (Anc Sci Life) Vol. 27 Issue 3 Pg. 36-40 (Jan 2008) ISSN: 0257-7941 [Print] India
• PMID: 22557276 (Publication Type: Journal Article)