Churg-Strauss syndrome related to montelukast.

Abstract

A young male with complaints of cough, dyspnea and hemoptysis was admitted. He was using fluticasone propionate and salmeterol for two years for his asthma. Leukotriene receptor antagonist was prescribed two weeks prior to his admission and no reduction of his inhaled steroid therapy was performed. Eosinophil count was detected as 1460/mm³ (15%) and immunoglobulin E level was 547 IU/mL. Thorax computerized tomography revealed patchy infiltration. Increased eosinophilic inflammation were detected in bronchoalveolar lavage fluid and transbronchial biopsy. He received prednisolone treatment for Churg-Strauss syndrome. Improvement was observed on three months follow up period. He has no complaint in his follow up.

• Authors: Meral Uyar, Osman Elbek, Kemal Bakır, Yasemin Kibar, Nazan Bayram, Öner Dikensoy
• Journal: Tuberkuloz ve toraks (Tuberk Toraks) Vol. 60 Issue 1 Pg. 56-8 ( 2012) ISSN: 0494-1373 [Print] Turkey
• PMID: 22554368 (Publication Type: Case Reports, Journal Article)

Chemical References

• Acetates
• Anti-Asthmatic Agents
• Cyclopropanes
• Leukotriene Antagonists
• Quinolines
• Sulfides
• montelukast

Topics

• Acetates (adverse effects, therapeutic use)
• Adolescent
• Anti-Asthmatic Agents (adverse effects)
• Asthma (drug therapy)
• Churg-Strauss Syndrome (chemically induced, diagnosis)
• Cough (chemically induced, diagnosis)
• Cyclopropanes
• Dyspnea (chemically induced, diagnosis)
• Hemoptysis (chemically induced, diagnosis)
• Humans
• Leukotriene Antagonists (adverse effects, therapeutic use)
• Male
• Quinolines (adverse effects, therapeutic use)
• Sulfides