Interaction of fibrinogen with murine melanoma cells: covalent association with cell membranes and protection against recognition by lymphokine-activated killer cells.

Abstract	B16/F10 melanoma cells, in a medium containing fibrinogen, form a coating of fibrin(ogen) on their surfaces. This coating is cross-linked in a manner characteristic of catalysis by cellular transglutaminase. The fibrin(ogen) coating on the surface of these tumor cells provides protection against the lytic effect of autologous lymphokine-activated killer cells.
Authors	M Cardinali, R Uchino, S I Chung
Journal	Cancer research (Cancer Res) Vol. 50 Issue 24 Pg. 8010-6 (Dec 15 1990) ISSN: 0008-5472 [Print] United States
PMID	2253243 (Publication Type: Journal Article)
Chemical References	Fibrinogen Putrescine
Topics	Animals Cell Membrane (immunology, metabolism) Electrophoresis, Polyacrylamide Gel Fibrinogen (isolation & purification, metabolism) Humans Killer Cells, Lymphokine-Activated (immunology) Kinetics Melanoma, Experimental (immunology, metabolism) Mice Putrescine (metabolism)

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