[Living birth after partial hysterectomy for chemorefractory gestational choriocarcinoma].

Abstract

Chemotherapy is the reference treatment for gestational trophoblastic neoplasia. In case of chemoresistance, hysterectomy has to be considered even in women wishing to conceive. A 31-year-old nulliparous patient presented a recurrent invasive mole, despite two regimens of chemotherapy. She underwent a partial uterine resection of an intramyometrial choriocarcinoma followed by a third-line regimen. Two years later she gave birth by cesarean section at 32 weeks of amenorrhea to a healthy child after a spontaneous pregnancy. In order to preserve patient's fertility, conservative uterine surgery is an alternative to hysterectomy for selected chemoresistant gestational trophoblastic neoplasia.

• Authors: F Couder, F Golfier, F Vaudoyer, J Massardier, J-P Guastalla, T Hajri, D Raudrant
• Journal: Gynecologie, obstetrique & fertilite (Gynecol Obstet Fertil) Vol. 40 Issue 6 Pg. 376-8 (Jun 2012) ISSN: 1769-6682 [Electronic] France
• Vernacular Title: Naissance vivante après hystérectomie partielle pour choriocarcinome gestationnel chimiorésistant.
• PMID: 22521990 (Publication Type: Case Reports, English Abstract, Journal Article)
• Copyright: Copyright © 2012 Elsevier Masson SAS. All rights reserved.

Topics

• Adult
• Cesarean Section
• Choriocarcinoma (drug therapy, surgery)
• Drug Resistance, Neoplasm
• Female
• Fertility Preservation (methods)
• Gestational Age
• Humans
• Hysterectomy
• Infant, Newborn
• Live Birth
• Pregnancy
• Uterine Neoplasms (drug therapy, surgery)
• Uterus (surgery)