Polyarthritis in four patients with chikungunya arthritis.

Abstract

The incidence of chikungunya infection in Singapore has been on the rise since the first reported case in 2006. Acute polyarthritis, a common manifestation among affected patients, may precede fever and present with debilitating arthritis to rheumatologists, orthopaedists, internists and primary care physicians. The diagnosis of chikungunya infection requires careful history taking and a high index of suspicion, with supporting evidence from the reverse transcription-polymerase chain reaction or the chikungunya IgM serology test. Treatment of chikungunya arthritis usually involves non-steroidal anti-inflammatory drugs. Rarely, polyarthritis in chikungunya may persist even after resolution of the acute infection, necessitating treatment with disease-modifying anti-rheumatic drugs. In this article, we present the different manifestations of chikungunya arthritis in our local setting and review the literature.

• Authors: Nai Lee Lui, Hoe Nam Leong, Julian Thumboo
• Journal: Singapore medical journal (Singapore Med J) Vol. 53 Issue 4 Pg. 241-3 (Apr 2012) ISSN: 0037-5675 [Print] India
• PMID: 22511045 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal

Topics

• Aged
• Alphavirus Infections (complications)
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Arthritis (drug therapy, virology)
• Chikungunya Fever
• Chikungunya virus
• Female
• Humans
• Male
• Middle Aged