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Neutropenic enterocolitis in a patient with ovarian cancer after treatment with high-dose carboplatin and granulocyte macrophage-colony stimulating factor (GM-CSF).

Abstract
A 50-yr-old women is described with relapsed ovarian cancer. She developed neutropenic enterocolitis after treatment with high-dose carboplatin (1000 mg/m2) and granulocyte macrophage-colony stimulating factor (GM-CSF). The clinical features and the pathogenesis of neutropenic enterocolitis are discussed. This case is the first report of neutropenic enterocolitis associated with the treatment of carboplatin.
AuthorsL T Vlasveld, W W Ten Bokkel Huinink, S Rodenhuis
JournalThe Netherlands journal of medicine (Neth J Med) Vol. 37 Issue 3-4 Pg. 158-61 (Oct 1990) ISSN: 0300-2977 [Print] Netherlands
PMID2250761 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Macrophage Colony-Stimulating Factor
  • Carboplatin
Topics
  • Antineoplastic Combined Chemotherapy Protocols (adverse effects)
  • Carboplatin (administration & dosage)
  • Combined Modality Therapy
  • Enterocolitis (chemically induced)
  • Female
  • Humans
  • Macrophage Colony-Stimulating Factor (administration & dosage)
  • Middle Aged
  • Neutropenia (chemically induced)
  • Ovarian Neoplasms (drug therapy)

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