Abstract | AIM: Conventional endoscopic mucosal resection (EMR) of carcinoid tumors is often associated with involvement of the resection margin, which necessitates further intervention. Endoscopic submucosal resection with a ligation device (ESMR-L) is a novel technique for the removal of carcinoid tumors. The aim of the present study was to compare the clinical usefulness of endoscopic submucosal resection with a ligation device with that of EMR for the complete resection of rectal carcinoid tumors. METHODS: Between January 2001 and October 2010, a total of 100 patients with 100 rectal carcinoid tumors that were estimated to be 10 mm or less in diameter and that were resected either using ESMR-L or EMR were recruited for this study. The complete resection rate and complications associated with these two procedures were analyzed. RESULTS: Forty-five out of 100 lesions were resected using ESMR-L, and 55 lesions were resected using EMR. Histopathologically, all tumors were free from lymphovascular and perineural invasion. The overall ESMR-L complete resection rate was higher than that of EMR (93.3% vs 65.5%, respectively, P = 0.001). Furthermore, the location of the tumors had no influence on the complete resection rate when ESMR-L was carried out, in contrast to the results of EMR. The procedure-related variables of procedure time and complication rate were not significantly different between the two groups. CONCLUSION: ESMR-L is a significantly superior modality to EMR for the complete removal of small rectal carcinoid tumors that are 10 mm or less in diameter.
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Authors | Hyung Hun Kim, Seun Ja Park, Sang Heon Lee, Hee Ug Park, Chul Soo Song, Moo In Park, Won Moon |
Journal | Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
(Dig Endosc)
Vol. 24
Issue 3
Pg. 159-63
(May 2012)
ISSN: 1443-1661 [Electronic] Australia |
PMID | 22507089
(Publication Type: Comparative Study, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
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Copyright | © 2011 The Authors. Digestive Endoscopy © 2011 Japan Gastroenterological Endoscopy Society. |
Topics |
- Carcinoid Tumor
(pathology, surgery)
- Endoscopy, Gastrointestinal
(methods)
- Female
- Hemostasis, Surgical
- Humans
- Intestinal Mucosa
(pathology, surgery)
- Ligation
(instrumentation)
- Male
- Middle Aged
- Rectal Neoplasms
(pathology, surgery)
- Republic of Korea
- Retrospective Studies
- Treatment Outcome
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