[Persistent candidemia in a renal-pancreatic transplant patient].

Abstract

BACKGROUND:

In recent decades, there has been an increase in the survival of recipients of solid organ transplants related to the improvement of the surgical technique, the introduction of protocols for immunosuppressive therapy, and the use of antimicrobial prophylaxis. Nonetheless, invasive fungal infection (IFI) is currently the major cause of morbidity and mortality in this group of patients. Invasive candidiasis is the most common IFI found after renal transplantation and is usually associated with total parenteral nutrition, broad-spectrum antibiotic therapy and abdominal surgery.

CLINICAL CASE:

We report the case of a recent kidney-pancreas transplant recipient who developed a persistent catheter-related candidemia caused by Candida glabrata. The patient was treated with anidulafungin and had a good clinical course with no significant drug interactions. We discuss the possible causes and diagnostic and therapeutic alternatives of this kind of infection.

• Authors: Miguel Solla-Buceta, Ana Hurtado-Doce, Luis Álvarez-Rocha
• Journal: Revista iberoamericana de micologia (Rev Iberoam Micol) 2012 Apr-Jun Vol. 29 Issue 2 Pg. 76-80 ISSN: 2173-9188 [Electronic] Spain
• Vernacular Title: Candidemia persistente en una paciente receptora de trasplante renopancreático.
• PMID: 22463781 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2012 Revista Iberoamericana de Micología. Published by Elsevier Espana. All rights reserved.

Topics

• Adult
• Candida glabrata
• Candidemia (drug therapy)
• Female
• Humans
• Kidney Transplantation
• Pancreas Transplantation
• Postoperative Complications (drug therapy)