Abstract |
As anaesthetists have become more aware of malignant hyperthermia the mortality rate has fallen, but concommitantly the number of dubious and aborted cases has increased. All probands who developed a suspected malignant hyperthermia reaction during anaesthesia and subsequently underwent muscle biopsy were classified according to the clinical presentation. A probability for malignant hyperthermia can be calculated, using the classification, for each type of clinical presentation; this varied from 0.96 to 0.07. Certain clinical features were found to be of more value as predictors than others; these included a high creative kinase and myoglobinuria. The accuracy of prediction depends on a clear contemporaneous description of the clinical events.
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Authors | F R Ellis, P J Halsall, A S Christian |
Journal | Anaesthesia
(Anaesthesia)
Vol. 45
Issue 10
Pg. 838-41
(Oct 1990)
ISSN: 0003-2409 [Print] England |
PMID | 2240497
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Creatine Kinase
(metabolism)
- Disease Susceptibility
- Humans
- Male
- Malignant Hyperthermia
(classification, metabolism, pathology)
- Masseter Muscle
(physiopathology)
- Muscles
(pathology)
- Myoglobinuria
(etiology)
- Probability
- Rhabdomyolysis
(metabolism)
- Spasm
(physiopathology)
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