Management of postoperative ileus.

Abstract

Postoperative ileus, a temporary cessation in bowel motility, is a common and significant complication of major surgery. Consequences of postoperative ileus include increased patient discomfort, delayed time to adequate nutrition, prolonged length of stay, and increased cost to the patient and healthcare system. The traditional, multi-modal approach to the resolution of postoperative ileus includes opioid minimization, early ambulation, and early feeding. Newer medications, such as methlynaltrexone and alvimopan (which are peripherally acting mu opioid receptor antagonists), have become available and have proven beneficial for use with postoperative ileus.

• Authors: Melissa Thompson, Barbara Magnuson
• Journal: Orthopedics (Orthopedics) Vol. 35 Issue 3 Pg. 213-7 (Mar 2012) ISSN: 1938-2367 [Electronic] United States
• PMID: 22385598 (Publication Type: Journal Article)
• Copyright: Copyright 2012, SLACK Incorporated.

Chemical References

• Gastrointestinal Agents
• Narcotic Antagonists
• Piperidines
• Quaternary Ammonium Compounds
• methylnaltrexone
• Naltrexone
• alvimopan

Topics

• Combined Modality Therapy
• Exercise Therapy (methods)
• Gastrointestinal Agents
• Humans
• Ileus (therapy)
• Naltrexone (analogs & derivatives, therapeutic use)
• Narcotic Antagonists
• Piperidines (therapeutic use)
• Postoperative Complications (therapy)
• Quaternary Ammonium Compounds (therapeutic use)