A case of myelolipoma with bilateral adrenal hyperaldosteronism cured after unilateral adrenalectomy.

Abstract

Myelolipomas are adrenal tumors composed of both adipose and hematopoietic tissues which are rarely associated with primary aldosteronism (PA). Here, we report a case of myelolipoma associated with PA. Aldosterone hypersecretion from bilateral adrenal glands had been confirmed by adrenal venous sampling and pathological analyses, but PA was clinically cured after surgical removal of the unilateral adrenal gland together with the myelolipoma that was not producing aldosterone. It is suggested that myelolipomas may release some factors which stimulate aldosterone production in adrenal glands, although further investigation is necessary. Obesity-related hyperaldosteronism might in part participate in generation of hypertension in the present case.

• Authors: Megumi Inuzuka, Naohisa Tamura, Masakatsu Sone, Daisuke Taura, Takuhiro Sonoyama, Kyoko Honda, Katsutoshi Kojima, Yorihide Fukuda, Yoriko Ueda, Yui Yamashita, Eri Kondo, Go Yamada, Toshihito Fujii, Masako Miura, Naotetsu Kanamoto, Akihiro Yasoda, Hiroshi Arai, Yoshiki Mikami, Hironobu Sasano, Kazuwa Nakao
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 51 Issue 5 Pg. 479-85 ( 2012) ISSN: 1349-7235 [Electronic] Japan
• PMID: 22382563 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Aldosterone

Topics

• Adrenal Gland Neoplasms (epidemiology, surgery)
• Adrenalectomy
• Aldosterone (metabolism)
• Comorbidity
• Humans
• Hyperaldosteronism (epidemiology, etiology, surgery)
• Hypertension (etiology)
• Male
• Middle Aged
• Myelolipoma (epidemiology, surgery)
• Obesity (complications)
• Treatment Outcome