Male partial hypogonadotrophic hypogonadism with gynaecomastia and metabolic syndrome.

Abstract

The causal association of childhood obesity and hypogonadotrophic hypogonadism needs to be studied to unravel the cause and effect relationship between the two conditions. The relationship of hypogonadism to the Metabolic Syndrome (MetS) remains valid even when using different definitions of MetS, and following the patients prospectively for over 10 years. This is a case of 19 years male who presented with micropenis, marked gynaecomastia and weight gain. Childhood obesity and family history of diabetes predisposed him to future MetS. Presence of micropenis reflects intrauterine hypogonadotrophic hypogonadism. Both entities exacerbated each other.

• Authors: Tasnim Ahsan, Zeenat Banu
• Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP (J Coll Physicians Surg Pak) Vol. 22 Issue 2 Pg. 105-7 (Feb 2012) ISSN: 1681-7168 [Electronic] Pakistan
• PMID: 22313648 (Publication Type: Case Reports, Journal Article)

Chemical References

• Gonadotropins
• Vitamin D
• Testosterone
• Metformin

Topics

• Follow-Up Studies
• Genital Diseases, Male (complications, diagnosis)
• Gonadotropins (metabolism)
• Gynecomastia (complications, diagnosis, drug therapy)
• Humans
• Hypogonadism (complications, diagnosis, drug therapy)
• Male
• Metabolic Syndrome (complications, diagnosis, therapy)
• Metformin (therapeutic use)
• Penis (abnormalities)
• Risk Assessment
• Severity of Illness Index
• Testosterone (therapeutic use)
• Treatment Outcome
• Vitamin D (therapeutic use)
• Young Adult