HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Sickle cell and renal transplant: a national survey and literature review.

Abstract
Sickle cell disease is an inherited, structural hemoglobin defect with multisystemic sequelae including renal failure. Patients with sickle cell disease are thought to benefit from renal transplant, but the long-term outcomes in such patients are unclear and have not been supported by any large prospective studies. Similarly, the renal morbidity and outcome after transplant in patients with sickle cell trait is also unclear. There is little evidence concerning living donation in donors with sickle cell disease or sickle cell trait, either for the donor health or for the graft outcome, and there are no United Kingdom guidelines. The aim of this study is to review the evidence surrounding renal transplant in recipients and donors with sickle syndromes and to determine the attitudes and current practices of United Kingdom transplant centers to performing such operations.
AuthorsJay Nath, James McDaid, Andrew Bentall, Simon Ball, Andrew R Ready, Nicholas G Inston
JournalExperimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation (Exp Clin Transplant) Vol. 10 Issue 1 Pg. 1-7 (Feb 2012) ISSN: 2146-8427 [Electronic] Turkey
PMID22309412 (Publication Type: Journal Article, Review)
Topics
  • Anemia, Sickle Cell (epidemiology, surgery)
  • Attitude of Health Personnel
  • Data Collection
  • Humans
  • Kidney Transplantation
  • Living Donors
  • Practice Patterns, Physicians'
  • Sickle Cell Trait (epidemiology, surgery)
  • Transplantation
  • United Kingdom (epidemiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: