Abstract | OBJECTIVE: METHODS: Children treated for primary testicular tumors between January 1998 and July 2010 were retrospectively analyzed. For yolk sac tumor, the difference of survival rates between patients with and without retroperitoneal lymph node dissection (RPLND) was calculated. RESULTS: Eighty-seven cases met our criteria and 78 were germ cell tumors, including 40 cases with yolk sac tumor. Patients were 3-128 months old (median 19), and 53 patients were diagnosed at younger than 2 years of age. For germ cell tumors, serum α- fetoprotein and β- human chorionic gonadotropin were elevated in 48 and 7 patients, respectively, including 38 and 2 in those with yolk sac tumor. RPLND and chemotherapy were performed in 13 and 19 patients, respectively, and surveillance was performed in 50 patients. With median follow-up of 50 months, 6 patients had recurrence, 4 patients died, and the others achieved complete remission. For stage I yolk sac tumor, the difference of survival rates between patients with and without RPLND was not significant (P = .808). CONCLUSION:
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Authors | Yun-Lin Ye, Xiang-Zhou Sun, Fu-Fu Zheng, Jun Bian, Yan-Ping Huang, Xue-Qi Zhang, Zhi-Xun Li, Ying Nie, Zi-Ke Qin, Yu-Ping Dai |
Journal | Urology
(Urology)
Vol. 79
Issue 4
Pg. 892-7
(Apr 2012)
ISSN: 1527-9995 [Electronic] United States |
PMID | 22305424
(Publication Type: Journal Article)
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Copyright | Copyright © 2012 Elsevier Inc. All rights reserved. |
Chemical References |
- Chorionic Gonadotropin
- alpha-Fetoproteins
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Topics |
- Adolescent
- Adrenal Rest Tumor
(therapy)
- Child
- Child, Preschool
- Chorionic Gonadotropin
(blood)
- Endodermal Sinus Tumor
(therapy)
- Humans
- Infant
- Kaplan-Meier Estimate
- Leydig Cell Tumor
(therapy)
- Lymph Node Excision
- Male
- Neoplasms, Germ Cell and Embryonal
(blood, mortality, surgery, therapy)
- Orchiectomy
- Rhabdomyosarcoma, Embryonal
(therapy)
- Testicular Neoplasms
(blood, mortality, surgery, therapy)
- alpha-Fetoproteins
(analysis)
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