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Application of an indoleamine 2,3-dioxygenase-expressing skin substitute improves scar formation in a fibrotic animal model.

AuthorsClaudia Chavez-Munoz, Ryan Hartwell, Reza B Jalili, Matthew Carr, Ruhangiz T Kilani, Seyed Mehdi Jafarnejad, Elham Rahmani-Neishabour, Farshad Forouzandeh, Steven T Boyce, Aziz Ghahary
JournalThe Journal of investigative dermatology (J Invest Dermatol) Vol. 132 Issue 5 Pg. 1501-5 (May 2012) ISSN: 1523-1747 [Electronic] United States
PMID22297642 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • Collagen Type I
  • Collagen Type I, alpha 1 Chain
  • Immunologic Factors
  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Matrix Metalloproteinase 1
Topics
  • Animals
  • Cicatrix (metabolism, pathology)
  • Collagen Type I (genetics, metabolism)
  • Collagen Type I, alpha 1 Chain
  • Fibroblasts
  • Gene Expression
  • Graft Survival
  • Immunologic Factors (genetics, metabolism)
  • Indoleamine-Pyrrole 2,3,-Dioxygenase (genetics, metabolism)
  • Matrix Metalloproteinase 1 (genetics, metabolism)
  • Rabbits
  • Skin (metabolism, pathology)
  • Skin, Artificial
  • Transduction, Genetic
  • Wound Healing

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