Segmental regeneration in right-lobe liver grafts in adult living donor liver transplant.
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| Abstract |
Our aim is to evaluate the relationship and impact of right-lobe (RL) liver grafts procured with or without the middle hepatic vein (MHV) trunk and MHV tributary reconstruction on segmental regeneration of these grafts in adult living donor liver transplantation (ALDLT). Patients underwent primary ALDLT using a RL liver graft were divided into three groups according to graft type: with MHV tributary reconstruction (group I), without MHV tributary reconstruction (group II), and with inclusion of the MHV trunk (group III). The overall graft volume and the volumes of the anterior and posterior segments of the grafts six months post-transplant, evaluated using computed tomography, were calculated as the regeneration indices. Optimal regeneration of the RL liver graft was achieved in the three groups of patients. There was no significant difference in the regeneration indices between groups I (149.4%) and III (143.6%). However, in group II (112.4%) without MHV or tributary reconstruction, the anterior regenerative index was lower than the other two groups and exhibited transient prolonged hyperbilirubinemia. Segmental graft regeneration is maximized by adequate venous drainage. Inclusion of the MHV trunk or MHV tributary reconstruction influences segmental liver regeneration and preclude transient hyperbilirubinemia in the early post-liver transplant phase.
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| Authors | Hsiu-Ling Chen, Leo Leung-Chit Tsang, Allan M Concejero, Tung-Liang Huang, Tai-Yi Chen, Hsin-You Ou, Chun-Yen Yu, Chao-Long Chen, Yu-Fan Cheng |
| Journal | Clinical transplantation (Clin Transplant) 2012 Sep-Oct Vol. 26 Issue 5 Pg. 694-8 ISSN: 1399-0012 [Electronic] Denmark |
| PMID | 22292888 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't) |
| Copyright | © 2012 John Wiley & Sons A/S. |
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