Surgical treatment of primary trigeminal neuralgia: comparison of the effectiveness between MVD and MVD+PSR in a series of 210 patients.

Abstract

AIM:

To evaluate the effectiveness of microvascular-decompression (MVD) or MVD+partial-sensory-rhizotomy (PSR) on the treatment of primary trigeminal neuralgia (TN).

MATERIAL AND METHODS:

210 TN patients were retrospectively studied, among which there're 142 cases underwent MVD and 68 cases underwent MVD+PSR.

RESULTS:

In MVD group, pain vanished in 128, obviously relieved in 9, and 137 cases were profited from MVD. In 82 cases with a follow-up over 2 years, pain vanished in 74, pain sometime occurred in 5 which could be relieved by oral medicine, 3 cases could not be controlled effectively by medicine. In MVD+PSR group, pain completely vanished in 67 cases, not changed in 1 case. In 47 cases with a follow-up over 2 years, pain sometime occurred in 2 which could be relieved by carbamazepine, the others were completely pain-free. The short-term pain-free rate of MVD+PSR group was obviously higher than MVD group(P < 0.05), after a follow-up over 2 years, the former was still higher than the later, 95.7% and 90.2% respectively, without significant difference in statistics.

CONCLUSION:

MVD+PSR was obviously superior to MVD in completely eliminating pain in short-term period after operation, however, longer pain-free rate need even longer time to follow up. Identifying the responsible vascular exactly and handling it reasonably were key to both groups.

• Authors: Liangwen Zhang, Yuan Zhang, Chao Li, Shugan Zhu
• Journal: Turkish neurosurgery (Turk Neurosurg) Vol. 22 Issue 1 Pg. 32-8 ( 2012) ISSN: 1019-5149 [Print] Turkey
• PMID: 22274968 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Analgesics, Non-Narcotic
• Carbamazepine

Topics

• Adult
• Aged
• Analgesics, Non-Narcotic (therapeutic use)
• Carbamazepine (therapeutic use)
• Cerebellum (blood supply)
• Cerebral Arteries (surgery)
• Decompression, Surgical (methods)
• Female
• Follow-Up Studies
• Functional Laterality
• Hemifacial Spasm (etiology)
• Humans
• Male
• Microsurgery (methods)
• Middle Aged
• Neurosurgical Procedures (methods)
• Pain (etiology)
• Pulsed Radiofrequency Treatment
• Retrospective Studies
• Rhizotomy (methods)
• Treatment Outcome
• Trigeminal Neuralgia (complications, surgery)